Simulation-based Surgical Planning

 Computer models unleash unprecedented predictive abilities and can guide cardiac surgery in the future to minimize uncertainty in patient outcomes, but must facilitate accurate yet quick simulations!

I combined a biomechanics simulation of a balloon-expandable TAVR deployment in a pre-operative personalized aorta model with ViCar3D CFD solver and a versatile + efficient prosthetic valve dynamics model from my PhD research to predict post-operative valve shape and associated hemodynamics.

Such simulations can rapidly provide a priori knowledge of valvular performance in different deployment configurations. This information enables clinicians to determine best deployment parameters and minimize future risks of structural as well as hemodynamic complications.

Credits:
TAV Deployment Simulation: Fateme Esmailie, Huang Chen & Lakshmi Dasi
Co-authors: Jung Hee Seo & Rajat Mittal